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High-Purity 7-Fluoro & 7-Substituted 1-Tetralones for Pharmaceutical & Fine Chemical Synthesis | |
7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-one (CAS: 2840-44-0) is a high-value fluorinated organic intermediate widely used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. As a member of the 1-tetralone family, it features a partially hydrogenated naphthalene core with a ketone functionality at the 1-position, providing a versatile scaffold for subsequent functional transformations. The incorporation of a fluorine atom at the 7-position profoundly influences the compound’s electronic properties, metabolic stability, and lipophilicity, making it a strategic building block in structure–activity relationship (SAR) studies and fluorine-containing drug design. Fluorinated compounds such as 7-Fluoro-1-tetralone often demonstrate enhanced bioavailability, receptor binding affinity, and metabolic resistance, attributes that make them indispensable in modern medicinal chemistry. The unique C–F bond introduces both steric and electronic effects, which can fine-tune molecular reactivity and improve the pharmacokinetic profiles of active pharmaceutical ingredients (APIs). UCHEM also supplies a full series of 7-substituted 1-tetralone analogues for comparative research and synthesis, including: 7-Methyl-1-tetralone (CAS: 22009-37-6) 7-Methoxy-1-tetralone (CAS: 6836-19-7) 7-Bromo-1-tetralone (CAS: 32281-97-3) 7-Chloro-1-tetralone (CAS: 26673-32-5) Each derivative offers distinct steric and electronic modulation, enabling chemists to explore diverse reactivity patterns and substitution effects. The methyl and methoxy analogues are frequently utilized in the synthesis of neuroactive agents, cardiovascular drugs, and fine chemical intermediates, while the halogenated derivatives (bromo and chloro) serve as key precursors for cross-coupling reactions such as Suzuki, Heck, or Buchwald–Hartwig coupling, expanding synthetic versatility toward complex molecules. UCHEM provides these intermediates with high purity, reliable quality control, and batch-to-batch consistency, supporting both laboratory-scale R&D and industrial manufacturing. With its comprehensive portfolio of fluorinated and halogenated tetralone derivatives, UCHEM enables researchers and process chemists to achieve efficient molecular optimization, scalable synthesis, and innovation in fluorine chemistry. | |
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| Target Nation: All Nations Target City : All Cities Last Update : 13 November 2025 7:24 AM Number of Views: 14 | Item Owner : Nina He Contact Email: Contact Phone: (None) |
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2025-11-13 (0.331 sec)