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Crown Ethers and Their Derivatives: Advanced Macrocyclic Compounds for Research and Industry


Crown ethers are a class of macrocyclic polyethers known for their exceptional ability to form stable complexes with alkali and alkaline earth metal ions. Among them, dicyclohexano-18-crown-6 (CAS: 16069-36-6)—also known as dicyclohexyl-18-crown-6 or DCH-18-crown-6—stands out as a versatile compound with wide-ranging applications across chemistry, biology, medicine, and materials science.

Dicyclohexano-18-crown-6: Structure and Applications
Dicyclohexano-18-crown-6 features an 18-membered ring consisting of repeating ethylene glycol units, with cyclohexyl groups attached at the 2, 3, 11, and 12 positions. These hydrophobic substituents enhance the compound’s solubility in organic solvents and improve its selectivity and binding strength for certain metal ions.

Applications include:
Chemistry:
Used as a powerful complexing agent, DCH-18-crown-6 facilitates the solubilization of alkali metal ions in non-polar solvents, enabling efficient phase-transfer catalysis and enhanced reaction kinetics in organic synthesis.

Biological Research:
Studied for its influence on ionic currents in neural systems, particularly at the node of Ranvier, where it modulates sodium and potassium ion permeability.

Medical/Nuclear Science:
Due to its strong affinity for metal ions such as Sr²⁺, it has been used in radiochemical separation processes—especially in the selective extraction of radioactive strontium from nuclear waste.

Industrial Applications:
Serves as a key intermediate in the development of ionic liquids, liquid crystals, and chemical vapor deposition (CVD) precursors.

Our Crown Ether Product Portfolio
We provide a wide range of high-purity crown ethers and their derivatives for laboratory, industrial, and pharmaceutical applications:
Benzo-12-crown-4 cas: 14174-08-4
Benzo-15-crown-5 cas: 14098-44-3
Benzo-18-crown-6 cas: 14098-24-9
Dibenzo-18-crown-6 CAS: 14187-32-7
Dicyclohexano-18-crown-6 cas: 16069-36-6
1,3-diisopropoxycalix[4!arenecrown-6 cas: 161282-96-8
4′,4″(5″)-Di-tert-butyldicyclohexano-18-crown-6 cas: 223719-29-7

These macrocyclic compounds offer unique selectivity profiles and can be customized for specific complexation, extraction, or sensor applications. All products are manufactured under strict quality control to ensure consistency, purity, and reproducibility.

Contact Us
If you're looking for crown ether compounds to support your R&D or manufacturing needs, we welcome your inquiries. Our team is ready to provide technical data, pricing, and delivery solutions tailored to your project.

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Last Update : 17 July 2025 10:50 AM
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Item  Owner  : Nina He
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