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Applications of Triethyloxonium Tetrafluoroborate CAS 368-39-8


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Triethyloxonium tetrafluoroborate (CAS: 368-39-8) is an important organic reagent with the molecular formula C6H15OBF4 and a molecular weight of 188.99 g/mol. It is a powerful ethylating agent, widely used in organic synthesis and research laboratories. Due to its high reactivity, this compound plays a key role in modifying functional groups and facilitating the formation of various organic intermediates.

Applications
Organic Synthesis
Triethyloxonium tetrafluoroborate is widely used to ethylate alcohols, phenols, carboxylic acids, and amines, producing esters, ethers, and alkylated derivatives. Its high reactivity makes it especially valuable in reactions where traditional alkylating agents are less efficient.

Pharmaceutical Research
In medicinal chemistry, this compound is employed to prepare drug intermediates and to modify bioactive molecules. The introduction of ethyl groups often enhances lipophilicity and improves the pharmacokinetic profile of potential therapeutic agents.

Catalysis and Materials Science
Triethyloxonium tetrafluoroborate is also explored in catalytic transformations and material modifications, where ethylation can alter surface properties and improve performance.

Safety and Handling
As a strong ethylating reagent, Triethyloxonium tetrafluoroborate must be handled with caution. It is moisture-sensitive and should be stored under dry, inert conditions. Appropriate personal protective equipment (PPE) is essential when working with this compound.

Conclusion
Triethyloxonium tetrafluoroborate (CAS: 368-39-8) is a versatile and powerful ethylating agent, essential in organic synthesis, pharmaceutical research, and materials science. UCHEM supplies high-quality Triethyloxonium tetrafluoroborate to support research and industrial needs worldwide.

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Last Update : 15 September 2025 10:57 AM
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